Cerebrospinal Fluid BACE1 Activity and Brain Amyloid Load in Alzheimer's Disease

The secretase BACE1 is fundamentally involved in the development of cerebral amyloid pathology in Alzheimer's disease (AD). It has not been studied so far to what extent BACE1 activity in cerebrospinal fluid (CSF) mirrors in vivo amyloid load in AD. We explored associations between CSF BACE1 ac...

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Detaylı Bibliyografya
Asıl Yazarlar: Grimmer, Timo, Alexopoulos, Panagiotis, Tsolakidou, Amalia, Guo, Liang-Hao, Henriksen, Gjermund, Yousefi, Behrooz H., Förstl, Hans, Sorg, Christian, Kurz, Alexander, Drzezga, Alexander, Perneczky, Robert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Scientific World Journal 2012
Konular:
Clinical Study
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259508/
https://ncbi.nlm.nih.gov/pubmed/22272179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/2012/712048
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