Cerebrospinal Fluid BACE1 Activity and Brain Amyloid Load in Alzheimer's Disease

The secretase BACE1 is fundamentally involved in the development of cerebral amyloid pathology in Alzheimer's disease (AD). It has not been studied so far to what extent BACE1 activity in cerebrospinal fluid (CSF) mirrors in vivo amyloid load in AD. We explored associations between CSF BACE1 ac...

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Bibliografiset tiedot
Päätekijät: Grimmer, Timo, Alexopoulos, Panagiotis, Tsolakidou, Amalia, Guo, Liang-Hao, Henriksen, Gjermund, Yousefi, Behrooz H., Förstl, Hans, Sorg, Christian, Kurz, Alexander, Drzezga, Alexander, Perneczky, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Scientific World Journal 2012
Aiheet:
Clinical Study
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259508/
https://ncbi.nlm.nih.gov/pubmed/22272179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/2012/712048
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