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Cerebrospinal fluid BACE1 activity and markers of amyloid precursor protein metabolism and axonal degeneration in Alzheimer’s disease

OBJECTIVE: To assess cerebrospinal fluid (CSF) β-site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) activity in relation to Alzheimer’s disease (AD) and to correlate the enzyme activity with protein markers of APP metabolism and axonal degeneration. METHODS: BACE1 activity and protein co...

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Библиографические подробности
Главные авторы: Perneczky, Robert, Alexopoulos, Panagiotis
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038661/
https://ncbi.nlm.nih.gov/pubmed/24239250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2013.09.006
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