Cerebrospinal Fluid BACE1 Activity and Brain Amyloid Load in Alzheimer's Disease

The secretase BACE1 is fundamentally involved in the development of cerebral amyloid pathology in Alzheimer's disease (AD). It has not been studied so far to what extent BACE1 activity in cerebrospinal fluid (CSF) mirrors in vivo amyloid load in AD. We explored associations between CSF BACE1 ac...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Grimmer, Timo, Alexopoulos, Panagiotis, Tsolakidou, Amalia, Guo, Liang-Hao, Henriksen, Gjermund, Yousefi, Behrooz H., Förstl, Hans, Sorg, Christian, Kurz, Alexander, Drzezga, Alexander, Perneczky, Robert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Scientific World Journal 2012
Gaiak:
Clinical Study
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259508/
https://ncbi.nlm.nih.gov/pubmed/22272179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/2012/712048
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