Cerebrospinal fluid biomarkers for Alzheimer’s disease: the role of apolipoprotein E genotype, age, and sex

INTRODUCTION: Cerebrospinal fluid (CSF) biomarkers improve the diagnostic accuracy for Alzheimer’s disease (AD), even at the predementia stage of the disease. The ε4-allele of apolipoprotein E (ApoE ε4), female sex, and older age are well-known risk factors for AD. It is unclear how these risk facto...

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Detalhes bibliográficos
Publicado no:Neuropsychiatr Dis Treat
Main Authors: Mehrabian, Shima, Alexopoulos, Panagiotis, Ortner, Marion, Traykov, Latchezar, Grimmer, Timo, Kurz, Alexander, Förstl, Hans, Bickel, Horst, Diehl-Schmid, Janine
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689289/
https://ncbi.nlm.nih.gov/pubmed/26719695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S95018
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