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Heteromers of amyloid precursor protein in cerebrospinal fluid

BACKGROUND: Soluble fragments of the amyloid precursor protein (APP) generated by α- and β-secretases, sAPPα and sAPPβ, have been postulated as promising new cerebrospinal fluid (CSF) biomarkers for the clinical diagnosis of Alzheimer’s disease (AD). However, the capacity of these soluble proteins t...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Cuchillo-Ibañez, Inmaculada, Lopez-Font, Inmaculada, Boix-Amorós, Alba, Brinkmalm, Gunnar, Blennow, Kaj, Molinuevo, Jose-Luis, Sáez-Valero, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298044/
https://ncbi.nlm.nih.gov/pubmed/25573162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-10-2
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