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Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer’s disease
BACKGROUND: The amyloid precursor protein (APP) is a transmembrane glycoprotein that undergoes alternative proteolytic processing. Its processing through the amyloidogenic pathway originates a large sAPPβ ectodomain fragment and the β-amyloid peptide, while non-amyloidogenic processing generates sAP...
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| Udgivet i: | Alzheimers Res Ther |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7425076/ https://ncbi.nlm.nih.gov/pubmed/32787955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00664-9 |
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