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The β-amyloid peptide compromises Reelin signaling in Alzheimer’s disease
Reelin is a signaling protein that plays a crucial role in synaptic function, which expression is influenced by β-amyloid (Aβ). We show that Reelin and Aβ oligomers co-immunoprecipitated in human brain extracts and were present in the same size-exclusion chromatography fractions. Aβ treatment of cel...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4987719/ https://ncbi.nlm.nih.gov/pubmed/27531658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31646 |
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