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Substrate Recognition Mechanism of VAMP/Synaptobrevin-cleaving Clostridial Neurotoxins
Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) inhibit neurotransmitter release by proteolyzing a single peptide bond in one of the three soluble N-ethylmaleimide-sensitive factor attachment protein receptors SNAP-25, syntaxin, and vesicle-associated membrane protein (VAMP)/synaptobrevi...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258937/ https://ncbi.nlm.nih.gov/pubmed/18511418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800610200 |
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