Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q(58)–K(59) Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities

In the recent past, about 40 botulinum neurotoxin (BoNT) subtypes belonging to serotypes A, B, E, and F pathogenic to humans were identified among hundreds of independent isolates. BoNTs are the etiological factors of botulism and represent potential bioweapons; however, they are also recognized pha...

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Библиографические подробности
Опубликовано в: :Toxins (Basel)
Главные авторы: Sikorra, Stefan, Skiba, Martin, Dorner, Martin B., Weisemann, Jasmin, Weil, Mirjam, Valdezate, Sylvia, Davletov, Bazbek, Rummel, Andreas, Dorner, Brigitte G., Binz, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6116196/
https://ncbi.nlm.nih.gov/pubmed/30071628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10080311
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