Clostridial Neurotoxins: Mechanism of SNARE Cleavage and Outlook on Potential Substrate Specificity Reengineering

Por Binz, Thomas, Sikorra, Stefan, Mahrhold, Stefan
Publicado em 2010

Substrate Recognition Mechanism of VAMP/Synaptobrevin-cleaving Clostridial Neurotoxins

Por Sikorra, Stefan, Henke, Tina, Galli, Thierry, Binz, Thomas
Publicado em 2008

Structural and biochemical characterization of the protease domain of the mosaic botulinum neurotoxin type HA

Por Lam, Kwok-ho, Sikorra, Stefan, Weisemann, Jasmin, Maatsch, Hannah, Perry, Kay, Rummel, Andreas, Binz, Thomas, Jin, Rongsheng
Publicado no Pathog Dis (2018)

Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission

Por Zanetti, Giulia, Sikorra, Stefan, Rummel, Andreas, Krez, Nadja, Duregotti, Elisa, Negro, Samuele, Henke, Tina, Rossetto, Ornella, Binz, Thomas, Pirazzini, Marco
Publicado no PLoS Pathog (2017)

Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q(58)–K(59) Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities

Por Sikorra, Stefan, Skiba, Martin, Dorner, Martin B., Weisemann, Jasmin, Weil, Mirjam, Valdezate, Sylvia, Davletov, Bazbek, Rummel, Andreas, Dorner, Brigitte G., Binz, Thomas
Publicado no Toxins (Basel) (2018)

Engineering an Effective Human SNAP-23 Cleaving Botulinum Neurotoxin A Variant

Por Sikorra, Stefan, Donald, Sarah, Elliott, Mark, Schwede, Susan, Coker, Shu-Fen, Kupinski, Adam P., Tripathi, Vineeta, Foster, Keith, Beard, Matthew, Binz, Thomas
Publicado no Toxins (Basel) (2020)