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Engineering an Effective Human SNAP-23 Cleaving Botulinum Neurotoxin A Variant
Botulinum neurotoxin (BoNT) serotype A inhibits neurotransmitter release by cleaving SNAP-25 and represents an established pharmaceutical for treating medical conditions caused by hyperactivity of cholinergic nerves. Oversecretion from non-neuronal cells is often also the cause of diseases. Notably,...
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| Publicado no: | Toxins (Basel) |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7766560/ https://ncbi.nlm.nih.gov/pubmed/33352834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12120804 |
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