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Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region
Hematopoietic stem cells (HSCs) emerge during embryogenesis and maintain hematopoiesis in the adult organism. Little is known about the embryonic development of human HSCs. We demonstrate that human HSCs emerge first in the aorta-gonad-mesonephros (AGM) region, specifically in the dorsal aorta, and...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256972/ https://ncbi.nlm.nih.gov/pubmed/22042975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111688 |
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