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Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region

Hematopoietic stem cells (HSCs) emerge during embryogenesis and maintain hematopoiesis in the adult organism. Little is known about the embryonic development of human HSCs. We demonstrate that human HSCs emerge first in the aorta-gonad-mesonephros (AGM) region, specifically in the dorsal aorta, and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ivanovs, Andrejs, Rybtsov, Stanislav, Welch, Lindsey, Anderson, Richard A., Turner, Marc L., Medvinsky, Alexander
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256972/
https://ncbi.nlm.nih.gov/pubmed/22042975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111688
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