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Identification of the Niche and Phenotype of the First Human Hematopoietic Stem Cells

In various vertebrate species, the dorsal aorta (Ao) is the site of specification of adult hematopoietic stem cells (HSCs). It has been observed that the upregulation of essential hematopoietic transcription factors and the formation of specific intra-aortic hematopoietic cell clusters occur predomi...

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Detalhes bibliográficos
Main Authors: Ivanovs, Andrejs, Rybtsov, Stanislav, Anderson, Richard A., Turner, Marc L., Medvinsky, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986508/
https://ncbi.nlm.nih.gov/pubmed/24749070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.02.004
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