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Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human Embryo

Definitive hematopoietic stem cells (HSCs) first emerge in the aorta-gonad-mesonephros (AGM) region in both mice and humans. An ex vivo culture approach has enabled recapitulation and analysis of murine HSC development. Knowledge of early human HSC development is hampered by scarcity of tissue: anal...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Easterbrook, Jennifer, Rybtsov, Stanislav, Gordon-Keylock, Sabrina, Ivanovs, Andrejs, Taoudi, Samir, Anderson, Richard A., Medvinsky, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525107/
https://ncbi.nlm.nih.gov/pubmed/30956115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.03.003
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