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Vast Self-Renewal Potential of Human AGM Region HSCs Dramatically Declines in the Umbilical Cord Blood

Human hematopoietic stem cells (HSCs) emerge in the aorta-gonad-mesonephros (AGM) region during Carnegie stages (CS) 14–17. Although we previously reported that these HSCs can generate no less than 300 daughter HSCs, their actual number has never been established. Here, we show that a single human A...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Ivanovs, Andrejs, Rybtsov, Stanislav, Anderson, Richard A., Medvinsky, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561509/
https://ncbi.nlm.nih.gov/pubmed/32946804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.08.008
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