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Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver

One day prior to mass emergence of haematopoietic stem cells (HSCs) in the foetal liver at E12.5, the embryo contains only a few definitive HSCs. It is thought that the burst of HSC activity in the foetal liver is underpinned by rapid maturation of immature embryonic precursors of definitive HSCs, t...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Rybtsov, Stanislav, Ivanovs, Andrejs, Zhao, Suling, Medvinsky, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852516/
https://ncbi.nlm.nih.gov/pubmed/27095492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.131193
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