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Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros–derived hematopoietic stem cells
Hematopoietic stem cells (HSCs) first emerge during embryonic development within vessels such as the dorsal aorta of the aorta-gonad-mesonephros (AGM) region, suggesting that signals from the vascular microenvironment are critical for HSC development. Here, we demonstrated that AGM-derived endotheli...
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| Vydáno v: | J Clin Invest |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463208/ https://ncbi.nlm.nih.gov/pubmed/25866967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80137 |
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