Discovery of a Novel Class of Orally Active Trypanocidal N-Myristoyltransferase Inhibitors

Lignende værker

• Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors
  af: Bayliss, Tracy, et al.
  Udgivet: (2017)
• Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode
  af: Spinks, Daniel, et al.
  Udgivet: (2015)
• Lead Optimization of a Pyrazole Sulfonamide Series of Trypanosoma bruceiN-Myristoyltransferase Inhibitors: Identification and Evaluation of CNS Penetrant Compounds as Potential Treatments for Stage 2 Human African Trypanosomiasis
  af: Brand, Stephen, et al.
  Udgivet: (2014)
• N-Myristoyltransferase inhibitors as new leads to treat sleeping sickness
  af: Frearson, Julie A., et al.
  Udgivet: (2010)
• A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors
  af: Harrison, Justin R., et al.
  Udgivet: (2018)