Wird geladen...
Nuclear PTEN regulates the APC-CDH1 tumor suppressive complex in a phosphatase-independent manner
PTEN is a frequently mutated tumor suppressor gene that opposes the PI3K-AKT pathway through dephosphorylation of phosphoinositide-3,4,5-triphosphate. Recently, nuclear compartmentalization of PTEN was found as a key component of its tumor suppressive activity, however its nuclear function remains p...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249980/ https://ncbi.nlm.nih.gov/pubmed/21241890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.12.020 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|