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PTEN level in tumor suppression: How much is too little?

The importance of PTEN (phosphatase and tensin homolog located on chromosome ten) in cancer has surpassed all predictions and expectations from the time it was discovered, and has qualified this gene as one of the most commonly mutated and deleted tumor suppressors in human cancer. PTEN levels are f...

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Detalhes bibliográficos
Main Authors: Carracedo, Arkaitz, Alimonti, Andrea, Pandolfi, Pier Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249925/
https://ncbi.nlm.nih.gov/pubmed/21266353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2488
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