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PTEN level in tumor suppression: How much is too little?

The importance of PTEN (phosphatase and tensin homolog located on chromosome ten) in cancer has surpassed all predictions and expectations from the time it was discovered, and has qualified this gene as one of the most commonly mutated and deleted tumor suppressors in human cancer. PTEN levels are f...

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Autori principali: Carracedo, Arkaitz, Alimonti, Andrea, Pandolfi, Pier Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249925/
https://ncbi.nlm.nih.gov/pubmed/21266353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2488
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