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PTEN level in tumor suppression: How much is too little?

The importance of PTEN (phosphatase and tensin homolog located on chromosome ten) in cancer has surpassed all predictions and expectations from the time it was discovered, and has qualified this gene as one of the most commonly mutated and deleted tumor suppressors in human cancer. PTEN levels are f...

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Bibliographic Details
Main Authors: Carracedo, Arkaitz, Alimonti, Andrea, Pandolfi, Pier Paolo
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249925/
https://ncbi.nlm.nih.gov/pubmed/21266353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2488
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