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Tobacco-specific carcinogen nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces AKT activation in head and neck epithelia

Exposure to tobacco carcinogens is causally associated with head and neck squamous cell carcinoma (HNSCC), but the underlying molecular mechanisms remain unclear. Here, we reported that AKT is activated at a higher frequency in both HNSCC tumors and the adjacent mucosa from HNSCC patients who are sm...

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Hlavní autoři: WEBER, STEPHEN M., BORNSTEIN, SOPHIA, LI, YUEXIN, MALKOSKI, STEPHEN P., WANG, DONNA, RUSTGI, ANIL K., KULESZ-MARTIN, MOLLY F., WANG, XIAO-JING, LU, SHI-LONG
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249931/
https://ncbi.nlm.nih.gov/pubmed/21822536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2011.1149
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