Binding with Nucleic Acids or Glycosaminoglycans Converts Soluble Protein Oligomers to Amyloid

Ample evidence suggests that almost all polypeptides can either adopt a native structure (folded or intrinsically disordered) or form misfolded amyloid fibrils. Soluble protein oligomers exist as an intermediate between these two states, and their cytotoxicity has been implicated in the pathology of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Di Domizio, Jeremy, Zhang, Ran, Stagg, Loren J., Gagea, Mihai, Zhuo, Ming, Ladbury, John E., Cao, Wei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Molecular Bases of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249128/
https://ncbi.nlm.nih.gov/pubmed/22102410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238477
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