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Endosomal Accumulation of the Activated Epidermal Growth Factor Receptor (EGFR) Induces Apoptosis

Endocytosis positively and negatively regulates cell surface receptor signaling by temporally and spatially controlling interactions with downstream effectors. This process controls receptor-effector communication. However, the relationship between receptor endocytic trafficking and cell physiology...

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Bibliografske podrobnosti
Main Authors: Rush, Jamie S., Quinalty, Leslie M., Engelman, Luke, Sherry, David M., Ceresa, Brian P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249126/
https://ncbi.nlm.nih.gov/pubmed/22102283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.294470
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