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Nanoconjugation Prolongs Endosomal Signaling of the Epidermal Growth Factor Receptor and Enhances Apoptosis

It is becoming increasingly clear that intracellular signaling can be subject to strict spatial control. As the covalent attachment of a signaling ligand to a nanoparticle (NP) impacts ligand-receptor binding, uptake, and trafficking, nanoconjugation provides new opportunities for manipulating intra...

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Bibliografiske detaljer
Udgivet i:Nanoscale
Main Authors: Wu, L., Xu, F., Reinhard, B.M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081566/
https://ncbi.nlm.nih.gov/pubmed/27378391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6nr02974d
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