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RAB7 and TSG101 are Required for the Constitutive Recycling of Unliganded EGFRs via Distinct Mechanisms
Both constitutive and ligand-mediated membrane trafficking regulate Epidermal Growth Factor Receptor (EGFR) signaling. The constitutive endocytosis and recycling of the unliganded EGFR is a critical determinant of cell surface EGFR expression and the cell’s sensitivity to ligands. We report that two...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831653/ https://ncbi.nlm.nih.gov/pubmed/23933150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2013.07.029 |
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