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RAB7 and TSG101 are Required for the Constitutive Recycling of Unliganded EGFRs via Distinct Mechanisms

Both constitutive and ligand-mediated membrane trafficking regulate Epidermal Growth Factor Receptor (EGFR) signaling. The constitutive endocytosis and recycling of the unliganded EGFR is a critical determinant of cell surface EGFR expression and the cell’s sensitivity to ligands. We report that two...

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Detalhes bibliográficos
Main Authors: Rush, Jamie S., Ceresa, Brian P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831653/
https://ncbi.nlm.nih.gov/pubmed/23933150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2013.07.029
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