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Protein-tyrosine Phosphatase 1B Modulates Early Endosome Fusion and Trafficking of Met and Epidermal Growth Factor Receptors

The endoplasmic reticulum-localized non-receptor protein-tyrosine phosphatase 1B (PTP1B) is associated with oncogenic, metabolic, and cytokine-related signaling and functionally targets multiple receptor tyrosine kinases (RTKs) for dephosphorylation. Loss of PTP1B activity leads to enhanced ligand-d...

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Bibliografiset tiedot
Päätekijät: Sangwan, Veena, Abella, Jasmine, Lai, Andrea, Bertos, Nicholas, Stuible, Matthew, Tremblay, Michel L., Park, Morag
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247994/
https://ncbi.nlm.nih.gov/pubmed/22045810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.270934
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