PTP1B Targets the Endosomal Sorting Machinery: DEPHOSPHORYLATION OF REGULATORY SITES ON THE ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT COMPONENT STAM2

Dephosphorylation and endocytic down-regulation are distinct processes that together control the signaling output of a variety of receptor tyrosine kinases (RTKs). PTP1B can directly dephosphorylate several RTKs, but it can also promote activation of downstream pathways through largely unknown mecha...

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Detalhes bibliográficos
Main Authors: Stuible, Matthew, Abella, Jasmine V., Feldhammer, Matthew, Nossov, Misha, Sangwan, Veena, Blagoev, Blagoy, Park, Morag, Tremblay, Michel L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911340/
https://ncbi.nlm.nih.gov/pubmed/20504764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115295
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