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PTP1B Regulates Cortactin Tyrosine Phosphorylation by Targeting Tyr(446)

The emergence of protein-tyrosine phosphatase 1B (PTP1B) as a potential drug target for treatment of diabetes, obesity, and cancer underlies the importance of understanding its full range of cellular functions. Here, we have identified cortactin, a central regulator of actin cytoskeletal dynamics, a...

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Sonraí Bibleagrafaíochta
Main Authors: Stuible, Matthew, Dubé, Nadia, Tremblay, Michel L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259645/
https://ncbi.nlm.nih.gov/pubmed/18387954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710534200
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