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PTP1B Regulates Cortactin Tyrosine Phosphorylation by Targeting Tyr(446)
The emergence of protein-tyrosine phosphatase 1B (PTP1B) as a potential drug target for treatment of diabetes, obesity, and cancer underlies the importance of understanding its full range of cellular functions. Here, we have identified cortactin, a central regulator of actin cytoskeletal dynamics, a...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259645/ https://ncbi.nlm.nih.gov/pubmed/18387954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710534200 |
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