Coordinated Regulation of Insulin Signaling by the Protein Tyrosine Phosphatases PTP1B and TCPTP

The protein tyrosine phosphatase PTP1B is a negative regulator of insulin signaling and a therapeutic target for type 2 diabetes. Our previous studies have shown that the closely related tyrosine phosphatase TCPTP might also contribute to the regulation of insulin receptor (IR) signaling in vivo (S....

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Bibliographische Detailangaben
Hauptverfasser: Galic, Sandra, Hauser, Christine, Kahn, Barbara B., Haj, Fawaz G., Neel, Benjamin G., Tonks, Nicholas K., Tiganis, Tony
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC543412/
https://ncbi.nlm.nih.gov/pubmed/15632081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.2.819-829.2005
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