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Epidermal Growth Factor Receptor and the Adaptor Protein p52(Shc) Are Specific Substrates of T-Cell Protein Tyrosine Phosphatase

T-cell protein tyrosine phosphatase (TCPTP) exists as two forms generated by alternative splicing: a 48-kDa endoplasmic reticulum (ER)-associated form (TC48) and a 45-kDa nuclear form (TC45). To identify TCPTP substrates, we have generated substrate-trapping mutants, in which the invariant catalytic...

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Detalhes bibliográficos
Main Authors: Tiganis, Tony, Bennett, Anton M., Ravichandran, Kodimangalam S., Tonks, Nicholas K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108877/
https://ncbi.nlm.nih.gov/pubmed/9488479
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