Regulation of Insulin Receptor Signaling by the Protein Tyrosine Phosphatase TCPTP

The human protein tyrosine phosphatase TCPTP exists as two forms: an endoplasmic reticulum-targeted 48-kDa form (TC48) and a nuclear 45-kDa form (TC45). Although targeted to the nucleus, TC45 can exit in response to specific stimuli to dephosphorylate cytoplasmic substrates. In this study, we invest...

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Main Authors: Galic, Sandra, Klingler-Hoffmann, Manuela, Fodero-Tavoletti, Michelle T., Puryer, Michelle A., Meng, Tzu-Ching, Tonks, Nicholas K., Tiganis, Tony
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149470/
https://ncbi.nlm.nih.gov/pubmed/12612081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.6.2096-2108.2003
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