Epidermal Growth Factor Receptor and the Adaptor Protein p52(Shc) Are Specific Substrates of T-Cell Protein Tyrosine Phosphatase

T-cell protein tyrosine phosphatase (TCPTP) exists as two forms generated by alternative splicing: a 48-kDa endoplasmic reticulum (ER)-associated form (TC48) and a 45-kDa nuclear form (TC45). To identify TCPTP substrates, we have generated substrate-trapping mutants, in which the invariant catalytic...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Tiganis, Tony, Bennett, Anton M., Ravichandran, Kodimangalam S., Tonks, Nicholas K.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1998
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108877/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488479/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.3.1622
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