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Dorsal Ruffle Microdomains Potentiate Met Receptor Tyrosine Kinase Signaling and Down-regulation

Dorsal ruffles are apical protrusions induced in response to many growth factors, yet their function is poorly understood. Here we report that downstream from the hepatocyte growth factor (HGF) receptor tyrosine kinase (RTK), Met, dorsal ruffles function as both a localized signaling microdomain as...

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Detalhes bibliográficos
Main Authors: Abella, Jasmine V., Parachoniak, Christine A., Sangwan, Veena, Park, Morag
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915731/
https://ncbi.nlm.nih.gov/pubmed/20529867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127985
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