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Met Kinase-dependent Loss of the E3 Ligase Cbl in Gastric Cancer

Strict regulation of signaling by receptor tyrosine kinases (RTKs) is essential for normal biological processes, and disruption of this regulation can lead to tumor initiation and progression. Signal duration by the Met RTK is mediated in part by the E3 ligase Cbl. Cbl is recruited to Met upon kinas...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lai, Andrea Z., Durrant, Michael, Zuo, Dongmei, Ratcliffe, Colin D. H., Park, Morag
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318713/
https://ncbi.nlm.nih.gov/pubmed/22262855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.339820
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