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Dorsal Ruffle Microdomains Potentiate Met Receptor Tyrosine Kinase Signaling and Down-regulation

Dorsal ruffles are apical protrusions induced in response to many growth factors, yet their function is poorly understood. Here we report that downstream from the hepatocyte growth factor (HGF) receptor tyrosine kinase (RTK), Met, dorsal ruffles function as both a localized signaling microdomain as...

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Detaylı Bibliyografya
Asıl Yazarlar: Abella, Jasmine V., Parachoniak, Christine A., Sangwan, Veena, Park, Morag
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915731/
https://ncbi.nlm.nih.gov/pubmed/20529867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127985
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