Met/Hepatocyte Growth Factor Receptor Ubiquitination Suppresses Transformation and Is Required for Hrs Phosphorylation

The Met receptor tyrosine kinase (RTK) regulates epithelial remodeling, dispersal, and invasion and is deregulated in many human cancers. It is now accepted that impaired down-regulation, as well as sustained activation, of RTKs could contribute to their deregulation. Down-regulation of the Met rece...

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Detalhes bibliográficos
Main Authors: Abella, Jasmine V., Peschard, Pascal, Naujokas, Monica A., Lin, Tong, Saucier, Caroline, Urbé, Sylvie, Park, Morag
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265818/
https://ncbi.nlm.nih.gov/pubmed/16227611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9632-9645.2005
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