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Met/Hepatocyte Growth Factor Receptor Ubiquitination Suppresses Transformation and Is Required for Hrs Phosphorylation

The Met receptor tyrosine kinase (RTK) regulates epithelial remodeling, dispersal, and invasion and is deregulated in many human cancers. It is now accepted that impaired down-regulation, as well as sustained activation, of RTKs could contribute to their deregulation. Down-regulation of the Met rece...

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Bibliografski detalji
Glavni autori: Abella, Jasmine V., Peschard, Pascal, Naujokas, Monica A., Lin, Tong, Saucier, Caroline, Urbé, Sylvie, Park, Morag
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265818/
https://ncbi.nlm.nih.gov/pubmed/16227611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9632-9645.2005
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