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Met/Hepatocyte Growth Factor Receptor Ubiquitination Suppresses Transformation and Is Required for Hrs Phosphorylation

The Met receptor tyrosine kinase (RTK) regulates epithelial remodeling, dispersal, and invasion and is deregulated in many human cancers. It is now accepted that impaired down-regulation, as well as sustained activation, of RTKs could contribute to their deregulation. Down-regulation of the Met rece...

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Bibliografiske detaljer
Main Authors: Abella, Jasmine V., Peschard, Pascal, Naujokas, Monica A., Lin, Tong, Saucier, Caroline, Urbé, Sylvie, Park, Morag
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265818/
https://ncbi.nlm.nih.gov/pubmed/16227611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9632-9645.2005
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