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Met/Hepatocyte Growth Factor Receptor Ubiquitination Suppresses Transformation and Is Required for Hrs Phosphorylation

The Met receptor tyrosine kinase (RTK) regulates epithelial remodeling, dispersal, and invasion and is deregulated in many human cancers. It is now accepted that impaired down-regulation, as well as sustained activation, of RTKs could contribute to their deregulation. Down-regulation of the Met rece...

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Main Authors: Abella, Jasmine V., Peschard, Pascal, Naujokas, Monica A., Lin, Tong, Saucier, Caroline, Urbé, Sylvie, Park, Morag
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265818/
https://ncbi.nlm.nih.gov/pubmed/16227611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9632-9645.2005
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