Different Epidermal Growth Factor Receptor (EGFR) Agonists Produce Unique Signatures for the Recruitment of Downstream Signaling Proteins

The EGF receptor can bind seven different agonist ligands. Although each agonist appears to stimulate the same suite of downstream signaling proteins, different agonists are capable of inducing distinct responses in the same cell. To determine the basis for these differences, we used luciferase frag...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ronan, Tom, Macdonald-Obermann, Jennifer L., Huelsmann, Lorel, Bessman, Nicholas J., Naegle, Kristen M., Pike, Linda J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786695/
https://ncbi.nlm.nih.gov/pubmed/26786109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710087
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