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Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress

Monocytes are key players in the immune system. Crossing the blood barrier, they infiltrate tissues and differentiate into (i) macrophages that fight off pathogens and (ii) dendritic cells (DCs) that activate the immune response. A hallmark of monocyte/macrophage activation is the generation of reac...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bauer, Martina, Goldstein, Michael, Christmann, Markus, Becker, Huong, Heylmann, Daniel, Kaina, Bernd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248544/
https://ncbi.nlm.nih.gov/pubmed/22160723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111919109
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