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Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress
Monocytes are key players in the immune system. Crossing the blood barrier, they infiltrate tissues and differentiate into (i) macrophages that fight off pathogens and (ii) dendritic cells (DCs) that activate the immune response. A hallmark of monocyte/macrophage activation is the generation of reac...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248544/ https://ncbi.nlm.nih.gov/pubmed/22160723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111919109 |
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