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Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress
Monocytes are key players in the immune system. Crossing the blood barrier, they infiltrate tissues and differentiate into (i) macrophages that fight off pathogens and (ii) dendritic cells (DCs) that activate the immune response. A hallmark of monocyte/macrophage activation is the generation of reac...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248544/ https://ncbi.nlm.nih.gov/pubmed/22160723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111919109 |
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