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Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress

Monocytes are key players in the immune system. Crossing the blood barrier, they infiltrate tissues and differentiate into (i) macrophages that fight off pathogens and (ii) dendritic cells (DCs) that activate the immune response. A hallmark of monocyte/macrophage activation is the generation of reac...

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Detalhes bibliográficos
Main Authors: Bauer, Martina, Goldstein, Michael, Christmann, Markus, Becker, Huong, Heylmann, Daniel, Kaina, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248544/
https://ncbi.nlm.nih.gov/pubmed/22160723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111919109
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