Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β

BACKGROUND: Amyloid β (Aβ) accumulates in Alzheimer's disease (AD) brain. Microglial activation also occurs in AD, and this inflammatory response may contribute to disease progression. Microglial activation can be induced by Aβ, but the mechanisms by which this occurs have not been defined. The...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kauppinen, Tiina M, Suh, Sang Won, Higashi, Youichirou, Berman, Ari E, Escartin, Carole, Won, Seok Joon, Wang, Chao, Cho, Seo-Hyun, Gan, Li, Swanson, Raymond A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2011
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247192/
https://ncbi.nlm.nih.gov/pubmed/22051244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-152
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