Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β

BACKGROUND: Amyloid β (Aβ) accumulates in Alzheimer's disease (AD) brain. Microglial activation also occurs in AD, and this inflammatory response may contribute to disease progression. Microglial activation can be induced by Aβ, but the mechanisms by which this occurs have not been defined. The...

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Bibliographische Detailangaben
Hauptverfasser: Kauppinen, Tiina M, Suh, Sang Won, Higashi, Youichirou, Berman, Ari E, Escartin, Carole, Won, Seok Joon, Wang, Chao, Cho, Seo-Hyun, Gan, Li, Swanson, Raymond A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247192/
https://ncbi.nlm.nih.gov/pubmed/22051244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-152
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