Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β

BACKGROUND: Amyloid β (Aβ) accumulates in Alzheimer's disease (AD) brain. Microglial activation also occurs in AD, and this inflammatory response may contribute to disease progression. Microglial activation can be induced by Aβ, but the mechanisms by which this occurs have not been defined. The...

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Detalhes bibliográficos
Main Authors: Kauppinen, Tiina M, Suh, Sang Won, Higashi, Youichirou, Berman, Ari E, Escartin, Carole, Won, Seok Joon, Wang, Chao, Cho, Seo-Hyun, Gan, Li, Swanson, Raymond A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247192/
https://ncbi.nlm.nih.gov/pubmed/22051244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-152
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