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Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β
BACKGROUND: Amyloid β (Aβ) accumulates in Alzheimer's disease (AD) brain. Microglial activation also occurs in AD, and this inflammatory response may contribute to disease progression. Microglial activation can be induced by Aβ, but the mechanisms by which this occurs have not been defined. The...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3247192/ https://ncbi.nlm.nih.gov/pubmed/22051244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-152 |
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