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In Vivo Sustained Release of siRNA from Solid Lipid Nanoparticles

Small interfering RNA (siRNA) is a highly potent drug in gene-based therapy with a challenge of being delivered in a sustained manner. Nanoparticle drug delivery systems allow for incorporating and controlled release of therapeutic payloads. We demonstrate that solid lipid nanoparticles can incorpor...

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Bibliografiske detaljer
Main Authors: Lobovkina, Tatsiana, Jacobson, Gunilla B., Gonzalez, Emilio Gonzalez, Hickerson, Robyn P., Leake, Devin, Kaspar, Roger L., Contag, Christopher H., Zare, Richard N.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246574/
https://ncbi.nlm.nih.gov/pubmed/22077198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn203745n
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