Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 achieves global cardiac gene transfer in canines

Achieving efficient cardiac gene transfer in a large animal model has proven to be technically challenging. Prior strategies have employed cardio-pulmonary bypass or dual catheterization with the aid of vasodilators to deliver vectors, such as adenovirus, adeno-associated virus or plasmid DNA. While...

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Main Authors: Bish, Lawrence T., Sleeper, Meg M., Brainard, Benjamin, Cole, Stephen, Russell, Nicholas, Withnall, Elanor, Arndt, Jason, Reynolds, Caryn, Davison, Ellen, Sanmiguel, Julio, Wu, Di, Gao, Guangping, Wilson, James M., Sweeney, H. Lee
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241935/
https://ncbi.nlm.nih.gov/pubmed/18813281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.202
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