Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 achieves global cardiac gene transfer in canines

Achieving efficient cardiac gene transfer in a large animal model has proven to be technically challenging. Prior strategies have employed cardio-pulmonary bypass or dual catheterization with the aid of vasodilators to deliver vectors, such as adenovirus, adeno-associated virus or plasmid DNA. While...

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Detalhes bibliográficos
Main Authors: Bish, Lawrence T., Sleeper, Meg M., Brainard, Benjamin, Cole, Stephen, Russell, Nicholas, Withnall, Elanor, Arndt, Jason, Reynolds, Caryn, Davison, Ellen, Sanmiguel, Julio, Wu, Di, Gao, Guangping, Wilson, James M., Sweeney, H. Lee
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241935/
https://ncbi.nlm.nih.gov/pubmed/18813281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.202
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