Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 achieves global cardiac gene transfer in canines

Achieving efficient cardiac gene transfer in a large animal model has proven to be technically challenging. Prior strategies have employed cardio-pulmonary bypass or dual catheterization with the aid of vasodilators to deliver vectors, such as adenovirus, adeno-associated virus or plasmid DNA. While...

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Détails bibliographiques
Auteurs principaux: Bish, Lawrence T., Sleeper, Meg M., Brainard, Benjamin, Cole, Stephen, Russell, Nicholas, Withnall, Elanor, Arndt, Jason, Reynolds, Caryn, Davison, Ellen, Sanmiguel, Julio, Wu, Di, Gao, Guangping, Wilson, James M., Sweeney, H. Lee
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241935/
https://ncbi.nlm.nih.gov/pubmed/18813281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.202
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